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  2. Carbidopa/levodopa - Wikipedia

    en.wikipedia.org/wiki/Carbidopa/levodopa

    Starting in late 2009 and continuing into 2011 Merck stopped manufacturing the drug while awaiting regulatory approvals due to a change in the supplier of the active ingredient. This resulted in shortages of the brand name products Sinemet and Sinemet CR, although alternative generic versions were still available. [25]

  3. Carbidopa - Wikipedia

    en.wikipedia.org/wiki/Carbidopa

    Carbidopa (Lodosyn) is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa.This property is significant in that it allows a greater proportion of administered levodopa to cross the blood–brain barrier for central nervous system effect, instead of being peripherally metabolised into substances unable to cross said barrier.

  4. Trihexyphenidyl - Wikipedia

    en.wikipedia.org/wiki/Trihexyphenidyl

    Trihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease.

  5. Follow the Money to These 2 Areas of Unmet Medical Needs

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  8. Teva Pharmaceuticals - Wikipedia

    en.wikipedia.org/wiki/Teva_Pharmaceuticals

    Teva's earliest predecessor was SLE, Ltd., a wholesale drug business founded in 1901 in Ottoman Empire's Mutasarrifate of Jerusalem.SLE Ltd. took its name from the initials of its three cofounders: Chaim Salomon, Moshe Levin and Yitschak Elstein, and used camels to make deliveries. [10]

  9. Levodopa-induced dyskinesia - Wikipedia

    en.wikipedia.org/wiki/Levodopa-induced_dyskinesia

    Levodopa-induced dyskinesia (LID) is a form of dyskinesia associated with levodopa (l-DOPA), used to treat Parkinson's disease.It often involves hyperkinetic movements, including chorea, dystonia, and athetosis.