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The process of spermatogenesis as the cells progress from primary spermatocytes, to secondary spermatocytes, to spermatids, to Sperm Cycle of the seminiferous epithelium of the testis. Spermatocytogenesis is the male form of gametocytogenesis and results in the formation of spermatocytes possessing half the normal complement of genetic material.
During spermatogenesis, the DNA of spermatogenic cells in the seminiferous tubules is subject to damage from such sources as reactive oxygen species. [1] The genomic integrity of spermatogenic cells is protected by DNA repair processes. [2] Deficiencies in the enzymes employed in these repair processes may lead to infertility. [2]
A spermatogonium (plural: spermatogonia) is an undifferentiated male germ cell.Spermatogonia undergo spermatogenesis to form mature spermatozoa in the seminiferous tubules of the testicles.
It is known that heterozygous chromosomal rearrangements lead to spermatogenic disturbance or failure; however the molecular mechanisms that cause this are not as well known. It is suggested that a passive mechanism involving asynaptic region clustering in spermatocytes is a possible cause.
Diagram of a human sperm cell. Sperm (pl.: sperm or sperms) is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one).
The second cell type is the cells belonging to the spermatogenic cell lineage. These eventually develop into sperm cells ( spermatozoon ). Typically, the spermatogenic cells will make four to eight layers in the germinal epithelium.
Animation of the migration of spermatozoa from their origin as germ cells to their exit from the vas deferens.A) Blood vessels; B) Head of epididymis; C) Efferent ductules; D) Seminiferous tubules; E) Parietal lamina of tunica vaginalis; F) Visceral lamina of tunica vaginalis; G) Cavity of tunica vaginalis; H) Tunica albuginea; I) Lobule of testis; J) Tail of epididymis; K) Body of epididymis ...
For those SSCs destined to form differentiating progenitor A1 spermatogonia (and hence spermatozoa), this is initiated at a defined stage during the spermatogenic cycle. [7] The precise location of SSCs throughout various staged cohorts of the seminiferous tubule determines their renewal function, to continuously produce progeny. [1]