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For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should not be initiated at the full replacement dose. [24] Since thyroid hormone increases the heart's oxygen demand by increasing heart rate and contractility, starting at higher doses may cause an acute coronary syndrome or an ...
Levothyroxine dosing to normalise TSH is based on the amount of residual endogenous thyroid function and the patient’s weight, particularly lean body mass. [15] The dose can be adjusted based upon each patient, for example, the dose may be lowered for elderly patients or patients with certain cardiac conditions, but should be increased in ...
Thyroid disease is a medical condition that affects the function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.
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Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]
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Thyroid hormones act on nearly every cell in the body. They act to increase the basal metabolic rate , affect protein synthesis , help regulate long bone growth (synergy with growth hormone ) and neural maturation, and increase the body's sensitivity to catecholamines (such as adrenaline ) by permissiveness . [ 12 ]
HGH supports several functions in the body — from growth, to muscle and bone strength, to the distribution of body fat, says Dr. Katie O'Sullivan, MD, an assistant professor of Adult & Pediatric ...
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