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Of them, 1,3,4-thiadiazole is the most common, appearing in such medications as cephazolin and acetazolamide. [ 1 ] [ 2 ] [ 3 ] In the Hurd-Mori reaction , an acyl hydrazone reacts with thionyl chloride or selenium dioxide to give a 1‑thia- or 1‑selena-2,3‑diazole.
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1,2,5-thiadiazole. 1,3,4-thiadiazole. Use as antifungal agents. Skeletal formula of fluconazole - an antifungal medication. The search for antifungal agents with ...
Thiazole (/ ˈ θ aɪ. ə z oʊ l /), or 1,3-thiazole, is a 5-membered heterocyclic compound that contains both sulfur and nitrogen. The term 'thiazole' also refers to a large family of derivatives. The term 'thiazole' also refers to a large family of derivatives.
1,2,3-benzothiadiazole is much less nucleophilic than naphthalene. Nitration is slow. [8] For that reason, many of its simple derivatives have been made from 2-aminothiophenols already having additional substituents. [7] 1,2,3-benzothiadiazole is a very weak base and alkylation reactions give exclusively the 3-amino quaternary salt. [9]
The Hurd–Mori 1,2,3-thiadiazole synthesis is a name reaction in organic chemistry that allows for the generation of 1,2,3-thiadiazoles through the reaction of hydrazone derivatives with an N-acyl or N-tosyl group reacted with thionyl chloride.
The following other wikis use this file: Usage on ar.wikipedia.org آزولات; ثياديازول; Usage on cs.wikipedia.org Azoly; Usage on eo.wikipedia.org
2,1,3-Benzothiadiazole has been of interest as a redox-active organic component in flow batteries owing to its favourable solubility, low reduction potential and fast electrochemical kinetics. [ 15 ] Such properties in derivatives containing this heterocycle have made it of growing interest in dyestuffs , [ 16 ] white light-emitting polymers ...