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Meckel's cartilage arises from the first pharyngeal arch. The dorsal end of each cartilage is connected with the ear-capsule and is ossified to form the malleus ; the ventral ends meet each other in the region of the mandibular symphysis , and are usually regarded as undergoing ossification to form that portion of the mandible which contains ...
In humans and other vertebrates, the pharyngeal arches are derived from all three germ layers (the primary layers of cells that form during embryonic development). [2] Neural crest cells enter these arches where they contribute to features of the skull and facial skeleton such as bone and cartilage. [2]
The mandibular prominence, or mandibular process is an embryological structure which gives rise to the lower portion of the face. The mandible and lower lip derive from it. [1] The mesenchymal cells within the mandibular prominence condense to form Meckel's cartilage. [2] It is innervated by the mandibular nerve. [3]
This cell potency means that some cells can be removed from the preimplantation embryo and the remaining cells will compensate for their absence. This has allowed the development of a technique known as preimplantation genetic diagnosis, whereby a small number of cells from the preimplantation embryo created by IVF, can be removed by biopsy and ...
The face and neck development of the human embryo refers to the development of the structures from the third to eighth week that give rise to the future head and neck.They consist of three layers, the ectoderm, mesoderm and endoderm, which form the mesenchyme (derived form the lateral plate mesoderm and paraxial mesoderm), neural crest and neural placodes (from the ectoderm). [1]
In the embryonic development of vertebrates, pharyngeal pouches form on the endodermal side between the pharyngeal arches. The pharyngeal grooves (or clefts) form the lateral ectodermal surface of the neck region to separate the arches.
By the tenth week, the portion of Meckel's cartilage which lies below and behind the incisor teeth is surrounded and invaded by the dermal bone (also known as the membrane bone). Somewhat later, accessory nuclei of cartilage make their appearance, as a wedge-shaped nucleus in the condyloid process and extending downward through the ramus;
In early fish and in chondrichthyans (cartilaginous fish such as sharks), Meckel's cartilage continued to be the main component of the lower jaw. But in the adult forms of osteichthyans (bony fish) and their descendants (amphibians, reptiles, birds and mammals) the cartilage was covered in bone – although in their embryos the jaw initially ...