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Xerostomia is the subjective sensation of dry mouth, which is often (but not always) associated with hypofunction of the salivary glands. [3] The term is derived from the Greek words ξηρός (xeros) meaning "dry" and στόμα (stoma) meaning "mouth". [4] [5] A drug or substance that increases the rate of salivary flow is termed a sialogogue.
During the European Age of Enlightenment, the belief that a "tooth worm" caused caries was also no longer accepted in the European medical community. [169] Pierre Fauchard, known as the father of modern dentistry, was one of the first to reject the idea that worms caused tooth decay and noted that sugar was detrimental to the teeth and gingiva ...
The condition is difficult to treat, and may involve fillings, fluoride to fight tooth decay and drugs that increase saliva for dry mouth, as well as oral hygiene instruction. It can be dangerous for active methamphetamine users to undergo dental surgery because of the cardiac problems that can result from the interaction of local anesthetic ...
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation.Hyposalivation often results in a dry mouth condition called xerostomia, and this can cause tooth decay due to the loss of the protective properties of saliva.
The decaying tooth root provides bacteria with an enclosed environment with low oxygen content. Consequently, the obligate and facultative anaerobes present within the oral cavity flourish and outcompete the other bacteria at the site of tooth decay, causing the dental caries to escalate into a mouth infection.
In a survey study of patients, many discontinued use because of discomfort, lack of efficacy or switching to CPAP, and frequent side-effects such as dry mouth, tooth pain, dental discomfort and jaw pain.
The bacteria gains access to the periapical region of the tooth through deeper infection of the pulp, traveling through the roots. The resulting pulpal necrosis causes proliferation of epithelial rests of Malassez which release toxins at the apex of the tooth. The body's inflammatory response will attack the source of the toxins, leading to ...
Along with S. sobrinus, S. mutans plays a major role in tooth decay, metabolizing sucrose to lactic acid. [2] [11] The acidic environment created in the mouth by this process is what causes the highly mineralized tooth enamel to be vulnerable to decay.
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