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Low-dose inhaled corticosteroids and formoterol maintenance therapy; Step 4: Daily symptoms, or waking with asthma once a week or more, and low lung function . Medium dose inhaled corticosteroids and formoterol maintenance therapy; Short-course oral corticosteroids when required in severely uncontrolled asthma
Both genes display some degree of polymorphic variation in humans, which may explain how some patients respond better to inhaled corticosteroid therapy than others. [14] [15] However, not all asthma patients respond to corticosteroids and large sub groups of asthma patients are corticosteroid resistant. [16]
Inhaled or nebulized corticosteroids can also be used. [151] For adults and children who are in the hospital due to acute asthma, systemic (IV) corticosteroids improve symptoms. [195] [196] A short course of corticosteroids after an acute asthma exacerbation may help prevent relapses and reduce hospitalizations. [197]
Beclometasone or beclomethasone, also known as beclomethasone dipropionate, and sold under the brand name Qvar among others, is a steroid medication. [1] It is available as an inhaler, cream, pills, and nasal spray. [2] The inhaled form is used in the long-term management of asthma. [1] The cream may be used for dermatitis and psoriasis. [3]
Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). [2] It contains budesonide, a steroid; and formoterol, a long-acting β 2-agonist (LABA). [2]
While the use of inhaled steroids and long-acting beta2‑adrenergic agonists are recommended for the resulting improvement in control of symptoms of asthma, [10] concerns have been raised that salmeterol may increase the risk of death due to asthma, and this additional risk is not reduced by the addition of inhaled steroids. [11]
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