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Although it contains 23% zinc and 77% L-carnosine by mass, [8] zinc carnosine is a molecule and not a mixture of zinc and L-carnosine. It is an approved drug requiring a medical prescription in Japan and South Korea where it is clinically used to treat gastric ulcers.
Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. [citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich. [1] Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine.
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
Zinc toxicity is a medical condition involving an overdose on, or toxic overexposure to, zinc. Such toxicity levels have been seen to occur at ingestion of greater than 50 mg of zinc. [1] [unreliable medical source?] Excessive absorption of zinc can suppress copper and iron absorption. The free zinc ion in solution is highly toxic to bacteria ...
Zinc deficiency is defined either as insufficient zinc to meet the needs of the body, or as a serum zinc level below the normal range. However, since a decrease in the serum concentration is only detectable after long-term or severe depletion, serum zinc is not a reliable biomarker for zinc status. [1]
The zinc oxide paste in the Unna’s Boot helps ease skin irritation and keeps the area moist. The zinc promotes healing within wound sites, making it useful for burns and ulcers. Zinc oxide paste is superior to gelatins used in other dressings, because it does not harden or cake. Some Unna Boots also contain calamine lotion and glycerin.
Therapy can include the use of zinc supplements to reduce the duration of diarrhea in infants and children under the age of 5. [1] Use of oral rehydration therapy has been estimated to decrease the risk of death from diarrhea by up to 93%. [2] Side effects may include vomiting, high blood sodium, or high blood potassium. [1]
Stress gastritis and ulcer prevention in critical care [18] Gastrinomas; Zollinger–Ellison syndrome (often 2–3× the regular dose is required) [19] Specialty professional organizations recommend that people take the lowest effective PPI dose to achieve the desired therapeutic result when used to treat gastroesophageal reflux disease long-term.