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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
Many children who become infected with EBV display no symptoms or the symptoms are indistinguishable from the other mild, brief illnesses of childhood. [21] When infection occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 to 50% of the time. [22] EBV infects B cells of the immune system and epithelial cells.
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
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The disease develops as a complication or progression of either Epstein–Barr virus-positive infectious mononucleosis (EPV+ IM) or chronic active Epstein–Barr virus infection (CAEBV)., [1] that is, as a worsening of the signs/symptoms some three weeks after the onset of an EBV+ IM-like disease or an any time during the course of CAEBV.
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Why some people recover from Lyme disease, while others experience months, years or even decades of chronic symptoms has long puzzled doctors. Why Lyme disease symptoms go away quickly for some ...
It will generally not be positive during the 4–6 week incubation period before the onset of symptoms. The highest amount of heterophile antibodies occurs 2 to 5 weeks after the onset of symptoms. [9] If positive, it will remain so for at least six weeks. [10] An elevated heterophile antibody level may persist up to 1 year. [9]