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Gout may be diagnosed and treated without further investigations in someone with hyperuricemia and the classic acute arthritis of the base of the great toe (known as podagra). Synovial fluid analysis should be done if the diagnosis is in doubt. [16] [50] Plain X-rays are usually normal and are not useful for confirming a diagnosis of early gout ...
A gout flare comes on suddenly, and symptoms are often intense. This will most commonly happen at night. Gout in foot joints is most common, with gout often affecting the big toe joint.
Gout is a form of inflammatory arthritis characterized by recurrent attacks ... Diagnosis may be confirmed by the presence of crystals in the joint fluid or in a ...
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
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When symptomatic, the disease classically begins with symptoms that are similar to a gout attack (thus the moniker pseudogout). These include: [citation needed] severe pain; warmth; swelling of one or more joints; severe fatigue; fever; feeling of malaise or flu-like symptoms; inability to walk or perform everyday tasks or hobbies
A 2011 survey in the United States indicated that 3.9% of the population had gout, whereas 21.4% had hyperuricemia without having symptoms. [ 43 ] Excess blood uric acid (serum urate) can induce gout , [ 44 ] a painful condition resulting from needle-like crystals of uric acid termed monosodium urate crystals [ 45 ] precipitating in joints ...
When uric acid levels and gout symptoms cannot be controlled with standard gout medicines that decrease the production of uric acid (e.g., allopurinol, febuxostat) or increase uric acid elimination from the body through the kidneys (e.g., probenecid), this can be referred to as refractory chronic gout (RCG). [3]