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There are many conditions comorbid to autism, such as attention deficit hyperactivity disorder, anxiety disorders, and epilepsy. In medicine, comorbidity is the presence of one or more additional conditions co-occurring with the primary one, or the effect of such additional disorders.
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
Multiple disabilities is a term for a person with a combination of disabilities, for instance, someone with both a sensory disability and a motor disability.Additionally, in the United States, it is a special education classification under which students are eligible for services through the Individuals with Disabilities Education Act, or IDEA. [1]
Autism spectrum disorder is a disorder of the many parts of the brain. Structural changes are observed in the cortex, which controls higher functions, sensation, muscle movements, and memory. Structural defects are seen in the cerebellum too, which affect the motor and communication skills. [14]
Baron-Cohen says that tests of the E–S model show that twice as many females than males are Type E and twice as many males than females are Type S. 65% of people with autism spectrum conditions are Extreme Type S. [6] The concept of the Extreme Type E brain has been proposed; however, little research has been conducted on this brain profile. [31]
The theory of the double empathy problem is a psychological and sociological theory first coined in 2012 by Damian Milton, an autistic autism researcher. [2] This theory proposes that many of the difficulties autistic individuals face when socializing with non-autistic individuals are due, in part, to a lack of mutual understanding between the two groups, meaning that most autistic people ...
These loss of function variants reduce function in the protein neurexin, which connects neurons at the synapse and is important for neurological development; deletion mutations of neurexin are also very common in people with autism, as well as other neurological disorders like schizophrenia, bipolar disorder, and ADHD.
The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.