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The original antigenic sin: When the body first encounters an infection it produces effective antibodies against its dominant antigens and thus eliminates the infection. But when it encounters the same infection, at a later evolved stage, with a new dominant antigen, with the original antigen now being recessive, the immune system will still produce the former antibodies against this old "now ...
Original antigenic sin; Vaccine adverse event; Other ways in which antibodies can (unusually) make an infection worse instead of better Blocking antibody, which can be either good or bad, depending on circumstances; Hook effect, most relevant to in vitro tests but known to have some in vivo relevances
This doctrine is known as the original antigenic sin. [21] This phenomenon comes into play particularly in immune responses against influenza , dengue and HIV viruses. [ 25 ] This limitation, however, is not imposed by the phenomenon of polyclonal response, but rather, against it by an immune response that is biased in favor of experienced ...
One model to explain this process is known as antibody-dependent enhancement (ADE), which allows for increased uptake and virion replication during a secondary infection with a different strain. Through an immunological phenomenon, known as original antigenic sin , the immune system is not able to adequately respond to the stronger infection ...
SPOILER ALERT: This post contains spoilers from the series premiere of Showtime’s “Dexter: Original Sin” now streaming on Paramount+. “Things were a little messy in the beginning…”
original antigenic sin. Also called antigenic imprinting and the Hoskins effect. The tendency of the human body's immune system to preferentially utilize immunological memory of a previous infection when a second, slightly different version of the pathogen (e.g. a virus or bacterium) is encountered in subsequent infections. The success of ...
What Is ‘Dexter: Original Sin’ About? Seacia Pavao/SHOWTIME According to the official plot summary, the prequel follows Dexter “as he transitions from student to avenging serial killer.”
Prepare for a killer holiday season. Dexter‘s prequel series Original Sin, which will follow the original show’s central character during his teenage years, will be available to stream on ...