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Although the results do not reflect the molecular events that occurred during early neural development or evolution, they provide insight into the molecular network that underlies the impaired cognitive and social scenarios that act in the schizophrenic brain, and further suggest that self-domestication, language processing, and schizophrenia ...
Thus, researchers hypothesize schizophrenia to be a homozygotic condition, and that asymptomatic heterozygotes are favored over average people. [17] Individuals with active symptoms of schizophrenia are more likely to seclude themselves from others, avoiding circumstances that may lead to excess amounts of stress or anxiety.
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
Symptoms of schizophrenia often appear soon after puberty, when the brain is undergoing significant maturational changes. Some investigators believe that the disease process of schizophrenia begins prenatally, remains dormant until puberty, then follows a period of neural degeneration that causes the symptoms to subsequently emerge. [13]
Rado proposed the term 'schizotype' to describe the person whose genetic make-up gave them a lifelong predisposition to schizophrenia. The quasi-dimensional model is so called because the only dimension it postulates is that of gradations of severity or explicitness in relation to the symptoms of a disease process: namely schizophrenia.
Schizophrenia affects around 0.3–0.7% of people at some point in their life. [ 19 ] [ 14 ] In areas of conflict this figure can rise to between 4.0 and 6.5%. [ 256 ] It occurs 1.4 times more frequently in males than females and typically appears earlier in men.
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
Interpretation of schizophrenia is a 756-page book divided in 45 chapters. Arieti begins his book stating that it is difficult to define schizophrenia. He asks if schizophrenia is an illness and answers in the negative, since the disorder is not understood in classic Virchowian criterion of cellular pathology.
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