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Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. [3] People may also experience feeling full earlier than expected when eating. [4] Indigestion is relatively common, affecting 20% of people at some point during their life, and is frequently caused by gastroesophageal reflux disease (GERD) or ...
Vomiting (the expulsion of gastric contents) is usually preceded by retching, but retching and vomiting can occur separately [6] and involve different sets of muscles. [7] During a retch, thoracic pressure is decreased and abdominal pressure is increased , which may serve to position gastric contents and overcome esophageal resistance. [ 6 ]
Nausea and vomiting associated with migraine headaches respond best to dopamine antagonists such as metoclopramide, prochlorperazine, and chlorpromazine. [22] In cases of gastroenteritis, serotonin antagonists such as ondansetron were found to suppress nausea and vomiting, as well as reduce the need for IV fluid resuscitation. [ 22 ]
Nausea in gastroparesis is usually postprandial, but morning or persistent nausea may occur. Vomiting is characterized by retching and forceful evacuation of gastric contents from the stomach up to and out of the mouth. Some patients may experience retching without gastric contents being expelled. [10]
One of the causes of abnormal bloating is excessive eating and air swallowing, known as aerophagia. [2] Other causes of bloating and distension include inflammatory bowel diseases such as Crohn's disease [3] [4] and ulcerative colitis, irritable bowel syndrome, diabetes, functional dyspepsia, or transient constipation.
[10] The medulla plays an important role for triggering the vomiting act. [11] The vomiting act encompasses three types of outputs initiated by the chemoreceptor trigger zone: Motor, parasympathetic nervous system (PNS), and sympathetic nervous system (SNS). They are as follows: Increased salivation to protect tooth enamel from stomach acids. [12]
Recovery phase is typically the phase where vomiting ceases, nausea diminishes or is absent, and appetite returns. "Cyclic vomiting syndrome (CVS) is a rare abnormality of the neuroendocrine system that affects 2% of children." [1] This disorder is thought to be closely related to migraines and family history of migraines. [2] [3]
Cannabinoid hyperemesis syndrome (CHS) is recurrent nausea, vomiting, and cramping abdominal pain that can occur due to prolonged, high-dose cannabis use. [4] [5]CHS is associated with frequent (weekly or more often), long-term (several months or longer) cannabis use; synthetic cannabinoids can also cause CHS.