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Bronchopulmonary dysplasia (BPD; part of the spectrum of chronic lung disease of infancy) is a chronic lung disease which affects premature infants. Premature (preterm) infants who require treatment with supplemental oxygen or require long-term oxygen are at a higher risk. [ 1 ]
Such small premature infants may remain ventilated for months. A study shows that an aerosol of a perfluorocarbon such as perfluoromethyldecalin can reduce inflammation in swine model of IRDS. [29] Chronic lung disease, including bronchopulmonary dysplasia, is common in severe RDS. The etiology of BPD is problematic and may be the result of ...
Wilson–Mikity syndrome, a form of chronic lung disease (CLD) that exists only in premature infants, leads to progressive or immediate development of respiratory distress. [ 2 ] [ 3 ] This rare condition affects low birth babies and is characterized by rapid development of lung emphysema after birth, requiring prolonged ventilation and oxygen ...
Pulmonary interstitial emphysema often resolves gradually and may take 2–3 weeks. [2] For longer durations of PIE the length of time of mechanical ventilation needed may increase and the incidence of bronchopulmonary dysplasia becomes higher. Some infants may develop chronic lobar emphysema, which may require surgical lobectomies. [3]
The "fetal origins hypothesis" suggests that the stress response of pre-term infants may underlie adult chronic diseases, possibly in relation to the hypothalamic-pituitary adrenal (HPA) axis. [6] Adverse health effects may be related to organs failing to achieve optimal development. [5]
The surge in children's respiratory illnesses, including rhinovirus and enterovirus, is pushing pediatric emergency departments and health systems toward capacity in some parts of the country.
In the 1980s, the development of pulmonary surfactant replacement therapy further improved survival of extremely premature infants and decreased chronic lung disease, one of the complications of mechanical ventilation, among less severely premature infants. [2]
Johnnie Walker, a former BBC Radio 2 DJ known for hosting the “Sounds of the 70s” show, died Monday. He was 79. The news was announced live on the station by Bob Harris, who took over Johnnie ...
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