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  2. Replication crisis - Wikipedia

    en.wikipedia.org/wiki/Replication_crisis

    The replication crisis does not necessarily mean these fields are unscientific. [16] [17] [18] Rather, this process is part of the scientific process in which old ideas or those that cannot withstand careful scrutiny are pruned, [19] [20] although this pruning process is not always effective. [21] [22]

  3. Reproducibility - Wikipedia

    en.wikipedia.org/wiki/Reproducibility

    Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.

  4. Hayflick limit - Wikipedia

    en.wikipedia.org/wiki/Hayflick_limit

    The typical normal human fetal cell will divide between 50 and 70 times before experiencing senescence. As the cell divides, the telomeres on the ends of chromosomes shorten. The Hayflick limit is the limit on cell replication imposed by the shortening of telomeres with each division. This end stage is known as cellular senescence.

  5. Replication - Wikipedia

    en.wikipedia.org/wiki/Replication

    Replication (scientific method), one of the main principles of the scientific method, a.k.a. reproducibility Replication (statistics), the repetition of a test or complete experiment; Replication crisis; Self-replication, the process in which an entity (a cell, virus, program, etc.) makes a copy of itself

  6. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    DNA replication is an all-or-none process; once replication begins, it proceeds to completion. Once replication is complete, it does not occur again in the same cell cycle. This is made possible by the division of initiation of the pre-replication complex. [citation needed]

  7. Postreplication repair - Wikipedia

    en.wikipedia.org/wiki/Postreplication_repair

    In this case, the term PRR would encompasses all processes that facilitate the replication of damaged DNA, including those that repair replication-induced double-strand breaks. Melanoma cells are commonly defective in postreplication repair of DNA damages that are in the form of cyclobutane pyrimidine dimers , a type of damage caused by ...

  8. Okazaki fragments - Wikipedia

    en.wikipedia.org/wiki/Okazaki_fragments

    Before this time, it was commonly thought that replication was a continuous process for both strands, but the discoveries involving E. coli led to a new model of replication. The scientists found there was a discontinuous replication process by pulse-labeling DNA and observing changes that pointed to non-contiguous replication.

  9. Backup - Wikipedia

    en.wikipedia.org/wiki/Backup

    The process of rearranging the sets of backups in an archive file is known as refactoring. For example, if a backup system uses a single tape each day to store the incremental backups for all the protected computers, restoring one of the computers could require many tapes.