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Biosafety level 4 laboratories are designed for diagnostic work and research on easily respiratory-acquired viruses which can often cause severe and/or fatal disease. What follows is a list of select agents that have specific biocontainment requirements according to US federal law.
A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. [1] These prevention mechanisms include the conduction of regular reviews of biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect from harmful incidents.
Laboratory Biosafety Manual, 3rd edition, 2004 [dead link ] (4th edition slideshow and draft - Section 8 on Laboratory Biosecurity) Laboratory Biosecurity Handbook. CRC Press. 2007. ISBN 978-0-8493-6475-4
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A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with (or potentially contaminated with) pathogens requiring a defined biosafety level.
The American Biological Safety Association (ABSA) was founded in 1984 to promote biosafety as a scientific discipline and to serve the growing needs of biosafety professionals throughout the world. Biosafety concerns the safe handling of biological materials, particularly infectious agents that cause risk to humans working with them.
Mycobacterium bovis is a slow-growing (16- to 20-hour generation time) aerobic bacterium and the causative agent of tuberculosis in cattle (known as bovine TB).It is related to Mycobacterium tuberculosis, the bacterium which causes tuberculosis in humans.