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2. GABA receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GABA_receptor_agonist

   Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

3. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   By the early 1970s, it was appreciated that there are two main classes of GABA receptors, GABA A and GABA B and also that baclofen was an agonist of GABA B receptors. Gabapentin was designed, synthesized and tested in mice by researchers at the pharmaceutical company Goedecke AG in Freiburg, Germany (a subsidiary of Parke-Davis ).

4. Gabapentinoid - Wikipedia

   en.wikipedia.org/wiki/Gabapentinoid

   [6] [12] Existing evidence on the use of gabapentinoids in chronic lower back pain is limited, and demonstrates significant risk of adverse effects, without any demonstrated benefit. [13] The main side-effects include: a feeling of sleepiness and tiredness, decreased blood pressure, nausea, vomiting and also glaucomatous visual hallucinations. [14]

5. Breakthrough antidepressants with fewer side effects could ...

   www.aol.com/finance/breakthrough-antidepressants...

   Allopregnanolone increases the activity of neurotransmitter GABA. “Where glutamate excites brain cells, GABA, the main inhibitory transmitter in the brain, tends to quiet them down,” Murrough ...

6. γ-Amino-β-hydroxybutyric acid - Wikipedia

   en.wikipedia.org/wiki/Γ-amino-β-hydroxybutyric...

   Relative to GABA, GABOB has more potent inhibitory effects on the central nervous system, perhaps due to its greater capacity to cross the blood–brain barrier. [ 5 ] [ 8 ] However, GABOB is of relatively low potency as an anticonvulsant when used by itself, and is more useful as an adjuvant treatment used alongside another anticonvulsant.

7. Ganaxolone - Wikipedia

   en.wikipedia.org/wiki/Ganaxolone

   Ganaxolone is thought to modulate both synaptic and extrasynaptic GABA A receptors to normalize over-excited neurons. [3] Ganaxolone's activation of the extrasynaptic receptor is an additional mechanism that provides stabilizing effects that potentially differentiates it from other drugs that increase GABA signaling. [3]

8. GABA reuptake inhibitor - Wikipedia

   en.wikipedia.org/wiki/GABA_reuptake_inhibitor

   A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]

9. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

   www.aol.com/terrible-amazing-side-effects-weight...

   GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now. GLP-1s ...