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The laser microtome is an instrument used for non-contact sectioning of biological tissues or materials. It was developed by the Rowiak GmbH, a spin-off of the Laser Centre, Hannover . In contrast to mechanically working microtomes , the laser microtome does not require sample preparation techniques such as freezing, dehydration or embedding.
A conceptual diagram of laser microtome operation. The laser microtome is an instrument for contact-free slicing. [22] Prior preparation of the sample through embedding, freezing or chemical fixation is not required, thereby minimizing the artifacts from preparation methods. Alternately this design of microtome can also be used for very hard ...
Laser-capture microdissection (LCM) is a method to procure subpopulations of tissue cells under direct microscopic visualization. LCM technology can harvest the cells of interest directly or can isolate specific cells by cutting away unwanted cells to give histologically pure enriched cell populations.
•Refrigerated microtome -do-; a special type that is used during operations to aid the surgeon in demarcating the diseased (specially neoplasms) tissue. •Rocking microtome-do-; a special type •Base sledge microtome-do-; a special type •Ultra microtome-do-; a special type Tissue section floating baths (in histopathology)
Pricier than its red laser cousin the GLL30, but more powerful into the bargain, this compact laser level will provide as much guidance as most DIY enthusiasts need, with the advantage of brighter ...
Fluorescence and confocal microscopes operating principle. Confocal microscopy, most frequently confocal laser scanning microscopy (CLSM) or laser scanning confocal microscopy (LSCM), is an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation. [1]
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