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These are achieved at lower doses, because many synthetic cannabinoids are more potent than marijuana, and users are often unaware of exactly what they are getting and how potent it is. [55] For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8]
Because the law limited only Δ 9-THC levels, many other cannabinoids are generally considered legal to sell and are widely available in stores and online, including Δ 8-THC, Δ 10-THC, HHC, and THCP, [68] [69] but have not had the same in-depth research that the Δ 9 isomer has on the human body; carrying potential risks in the short- or long ...
Cannabis in Ohio is legal for recreational use. Issue 2 , a ballot measure to legalize recreational use , passed by a 57–43 margin on November 7, 2023. Possession and personal cultivation of cannabis became legal on December 7, 2023.
The legal cannabis industry in New York is expected to soar in 2025, with state regulators projecting the number of new licensed pot stores will more than double from 275 to more than 625.
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Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
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Cannabis Station, a medical cannabis dispensary in Denver, Colorado Cannabis flower stored in jars at a dispensary in Colorado. Cannabis dispensaries in the United States or marijuana dispensaries are a type of cannabis retail outlet, local government-regulated physical location, typically inside a retail storefront or office building, in which a person can purchase cannabis and cannabis ...