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The gray matter remains normal in all characteristics while the white matter changes texture, becoming soft and gelatinous. Rarefaction of the white matter is seen through light microscopy and the small number of axons and U-fibers that were affected can also be seen. Numerous small cavities in the white matter are also apparent.
A metabolism disorder or tumors in the nervous system may appear to be CP; metabolic disorders, in particular, can produce brain problems that look like CP on an MRI. [1] Disorders that deteriorate the white matter in the brain and problems that cause spasms and weakness in the legs, may be mistaken for CP if they first appear early in life. [96]
[4] Future researchers should focus on using superior diffusion imaging methods as well correlating specific symptoms, rather than presence or absence of disease state, with changes in white matter. [4] In contrast, microstructural changes to the uncinate fasciculus have been consistently been linked to conduct disorder and psychopathy. [15]
Disconnection syndrome is a general term for a collection of neurological symptoms caused – via lesions to associational or commissural nerve fibres – by damage to the white matter axons of communication pathways in the cerebrum (not to be confused with the cerebellum), independent of any lesions to the cortex. [1]
While all leukodystrophies are the result of genetic mutations, [3] other demyelinating disorders have an autoimmune, infectious, or metabolic etiology. [4] When damage occurs to white matter, subsequent immune responses can lead to inflammation in the central nervous system (CNS), along with the loss of myelin.
Chopra says Rodgers was immediately “really trusting” with him and Hughes, adding that throughout their year working together on the documentary, Rodgers “was very open and vulnerable.”
The white matter in preterm born children is particularly vulnerable during the third trimester of pregnancy when white matter developing takes place and the myelination process starts around 30 weeks of gestational age.
But records matter, too, especially for players toiling on teams without championship aspirations. Here are 10 that might go down in the coming weeks: Rushing yards, single season.