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In particular, bronchoalveolar lavage is commonly used to diagnose infections in people with immune system problems, [12] pneumonia in people on ventilators, [5] [6] and acute respiratory distress syndrome (ARDS).
Pneumonia is an inflammatory condition of the lung primarily ... and Chlamydia can also be detected using PCR techniques on bronchoalveolar lavage and ...
Bronchoalveolar lavage with lymphocytosis; Lung biopsy consistent with pneumonitis histopathology; Exposure to causative agents of pneumonitis in a specific environment can be confirmed through aero/microbiologic analysis to verify its presence. Subsequent testing of patient serum for evidence of serum specific IgG antibodies confirms patient ...
The bronchoalveolar lavage in organizing pneumonia shows a lymphocytic predominant inflammation of the alveoli with increases in neutrophils and eosinophils. [9] Resolution of inflammatory cells in the bronchoalveolar lavage is usually delayed in organizing pneumonia, lagging behind clinical and radiographic improvement. [9]
The diagnosis can be definitively confirmed by histological identification of the causative organism in sputum or bronchoalveolar lavage (lung rinse). Staining with toluidine blue, silver stain, periodic acid-Schiff stain, or an immunofluorescence assay shows the characteristic cysts. [13]
Whole lung lavage (WLL), also called lung washing, is a medical procedure in which the patient's lungs are washed with saline (salt water) by filling and draining repeatedly. It is used to treat pulmonary alveolar proteinosis , in which excess lung surfactant proteins prevent the patient from breathing.
Since laboratory testing, imaging, and bronchoalveolar lavage results are often non-specific, guidelines recommend surgical biopsy to diagnose desquamative interstitial pneumonia if high-resolution computed tomography does not reveal classic signs of interstitial pneumonia. [17] A definitive diagnosis of DIP relies on a lung biopsy. [18]
Lung washings or tissue for histopathologic analysis are most commonly obtained using bronchoalveolar lavage and/or lung biopsy. [13] Characteristic biopsy findings show filling of the alveoli (and sometimes terminal bronchioles) with an amorphous eosinophilic material, which stains strongly positive on PAS stain and the PAS diastase stain.