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Bronchoalveolar lavage (BAL), also known as bronchoalveolar washing, is a diagnostic method of the lower respiratory system in which a bronchoscope is passed through the mouth or nose into an appropriate airway in the lungs, with a measured amount of fluid introduced and then collected for examination.
Lipid-laden alveolar macrophages, also known as pulmonary foam cells, [2] are cells found in bronchoalveolar lavage (BAL) specimens that consist of macrophages containing deposits of lipids (fats). [3] The lipid content of the macrophages can be demonstrated using a lipid targeting stain like Oil Red O or Nile red.
In a mice model of ovalbumin-induced allergic airway disease, 12-HHT and its companion cyclooxygenase metabolites, prostaglandin E 2 and prostaglandin D 2, but not 12 other lipoxygenase or cycloxygenase metabolites, showed a statistically significantly increase in bronchoalveolar lavage fluid levels after intratracheal ovalbumin challenge ...
BLT2 receptor knockout mice exhibit attenuated ovalbumen-induced allergic airway eosinophilia and interleukin 13 (IL-13) content in their bronchoalveolar lavage fluid compared with wild type mice and CD4-positive T cells isolated from the knockout mice showed a reduction IL-13 production but there was no change in the bronchospasm response to ...
Lung washings or tissue for histopathologic analysis are most commonly obtained using bronchoalveolar lavage and/or lung biopsy. [13] Characteristic biopsy findings show filling of the alveoli (and sometimes terminal bronchioles) with an amorphous eosinophilic material, which stains strongly positive on PAS stain and the PAS diastase stain.
This study showed that itaconate stimulated the nasal secretion of mucus when applied to the noses of mice, reduced the number of Pseudomonas aeruginosa bacteria in their lung tissue and bronchoalveolar lavage fluid (i.e., airway washing) in mice injected intranasally with these bacteria, and stimulated cultured mouse respiratory epithelium ...
Bronchoalveolar lavage (BAL) is a well-tolerated diagnostic procedure in ILD. [11] BAL cytology analyses (differential cell counts) should be considered in the evaluation of patients with IPF at the discretion of the treating physician based on availability and experience at their institution.
In a mouse model of asthma (i.e. hypersensitivity to ovalabumin), a TP receptor antagonist decreased the number of eosinophils infiltrating lung as judged by their content in Bronchoalveolar lavage fluid and in a mouse model of dust mite-induced astha, deletion of TBXA2R prevented the development of airways contraction and pulmonary ...