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Women with vasomotor symptoms during menopause seem to have an especially unfavorable cardiometabolic profile, [36] as well as women with premature onset of menopause (before 45 years of age). [37] These risks can be reduced by managing risk factors, such as tobacco smoking, hypertension, increased blood lipids and body weight. [38] [39]
Menopause is a natural biological process. For some, it happens in their 40s while others start later in life in their 50s (the average age is 51 in the United States, according to Mayo Clinic).
"Hot flashes and night sweats, also known as vasomotor symptoms, occur due in part to low estrogen effects on the thermoregulatory center of the brain, narrowing the window of comfortable ...
On 28 June 2013 FDA approved Brisdelle (low-dose paroxetine mesylate) for the treatment of moderate-to-severe vasomotor symptoms (e.g. hot flashes and night sweats) associated with menopause. Paroxetine became the first and only non-hormonal therapy for menopausal hot flashes approved by FDA. [29]
Vasomotor symptoms tend to be especially bothersome at night, leading to frequent wake-ups, which is one reason why many perimenopausal women report fatigue. Read More: How to Deal With Menopause ...
In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system. Hypoestrogenism is most commonly found in women who are postmenopausal , have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods ).
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