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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
Cervical cancer is the 12th-most common cancer in women in the UK (around 3,100 women were diagnosed with the disease in 2011) and accounts for 1% of cancer deaths (around 920 died in 2012). [154] With a 42% reduction from 1988 to 1997, the NHS-implemented screening programme has been highly successful, screening the highest-risk age group (25 ...
The risk of disease progression and metastasis (spread of the cancer) may be increased, but this increase risk appears to be small if the program of surveillance is followed closely, generally including serial PSA assessments and repeat prostate biopsies every 1–2 years depending on the PSA trends.
Cervical cancer is a type of gynecological cancer that begins from cells lining the cervix, the lower part of the uterus. [14] Cervical cancer begins when the cells that line the cervix become abnormal and grow in a pattern that is atypical for non-cancerous cells. [14] Cervical cancer is typically first identified with an abnormal pap smear. [14]
PAP immunohistochemical staining is often used with PSA (staining), by pathologists, to help distinguish poorly differentiated carcinomas.For example, poorly differentiated prostate adenocarcinoma (prostate cancer) and urothelial carcinoma (bladder cancer) may appear similar under the microscope, but PAP and PSA staining can help differentiate them; [7] prostate adenocarcinoma often stains ...
Prostate cancer is the second-most frequently diagnosed cancer in men, and the second-most frequent cause of cancer death in men (after lung cancer). [ 2 ] [ 3 ] Around 1.2 million new cases of prostate cancer are diagnosed each year, and over 350,000 people die of the disease, annually. [ 2 ]
The Cervical Cancer gene DataBase (CCDB) is a database of genes involved in the cervical carcinogenesis. [1] The Cervical Cancer Database is the first database that has been manually curated. [ 2 ] The database serves as an entity for clinicians and researchers to examine basic information as well as advanced information about the genes that ...
Cancer screening. Pap smear or liquid-based cytology to detect potentially precancerous lesions and prevent cervical cancer; Mammography to detect breast cancer; Colonoscopy and fecal occult blood test to detect colorectal cancer; Dermatological check to detect melanoma; PSA to detect prostate cancer; PPD test to screen for exposure to tuberculosis