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Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 inhibitor, used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast cancer. [12] [14] [15] [16] It is administered by slow intravenous ...
Fatty liver disease happens when fat builds up in your liver. This can cause damage, inflammation, and other complications. Fatty Liver Disease: What Men Need to Know
[64] [8] [136] [137] [135] Aside from men with prostate cancer, liver changes have also been observed in women treated with low doses of bicalutamide (10–50 mg/day) for scalp hair loss. [138] Rates of elevated liver enzymes have ranged from 2.9 to 11.4% in these studies, which spontaneously resolved in some women and necessitated ...
Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was developed by Merck and first approved by the Food and Drug Administration in 2014 for the treatment of melanoma. It was later approved for metastatic non-small cell lung cancer and head and neck squamous cell carcinoma. In 2017, it became the first immunotherapy drug approved for ...
New research has found that six herbal supplements that are popular on TikTok may cause liver damage. Researchers at the University of Michigan concluded that supplements, including Ashwagandha ...
"The data does not allow a definitive answer, and there also appears to be significant variation among people in their susceptibility to liver damage from green tea," Dr. Clarke points out.
Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.
Different stages of liver damage. Fatty liver (FL) is commonly associated with metabolic syndrome (diabetes, hypertension, obesity, and dyslipidemia), but can also be due to any one of many causes: [14] [15] Alcohol Alcohol use disorder is one of the causes of fatty liver due to production of toxic metabolites like aldehydes during metabolism ...
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