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Lymphocyte: B cell: MBC; 8-10 Memorizes the characteristics of the antigens; Triggers an accelerated and robust secondary immune response [4] [16] Killer T cell: Lymphocyte: T cell: T lymphocyte; Lymphocytus T; 8-10 Virus-infected cells; Cancer cells; Recruits and communicates with other types of immune cells [4] [17] Memory T cell: Lymphocyte ...
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
The coordinated expression of these specific transcription factors activate or repress target genes critical in the differentiation of the lymphocyte subsets. [27] In particular, Nfil3, whose expression is regulated by cytokines, controls the differentiation of ILCs via the transcription factors Id2, RORγt, Eomes, and Tox . [ 29 ]
ILC3 cells produce cytokines typical for the population of Th17 helper lymphocytes. The characteristic feature of ILC3 is the expression of the RORγt transcription factor, which is needed for its development and expression of the chemokine receptor CCR6. [2] This group of ILC produces IL-17 (especially IL-17A) [4] and IL-22. [5]
A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus. [1] These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.
Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies. Important lymphokines secreted by the T helper cell include: [2] Interleukin 2; Interleukin 3; Interleukin 4; Interleukin 5 ...
The presence of CD69 is not specific for T h 3 cells, since it is expressed on other lymphocytes, mainly subsets that are tissue resident. [8] The latency-associated peptide (LAP) noncovalently bounds TGF-β and can be expressed by many cells of the immune system. [9] In tumors T h 3 cells can express lymphocyte activation gene-3 (LAG3).
B1 cells are a sub-class of B cell lymphocytes that are involved in the humoral immune response.They are not part of the adaptive immune system, as they have no memory, but otherwise, B1 cells perform many of the same roles as other B cells: making antibodies against antigens and acting as antigen-presenting cells.