enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Natural killer cell - Wikipedia

    en.wikipedia.org/wiki/Natural_killer_cell

    Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system.They are a kind of large granular lymphocytes [1] [2] (LGL), and belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. [3]

  3. MHC class I polypeptide–related sequence A - Wikipedia

    en.wikipedia.org/wiki/MHC_class_I_polypeptide...

    MICA rather functions as a stress-induced ligand (as a danger signal) for integral membrane protein receptor NKG2D ("natural-killer group 2, member D"). MICA is broadly recognized by NK cells, γδ T cells, and CD8 + αβ T cells which carry NKG2D receptor on their cell surface and which are activated via this interaction. [7]

  4. KLRC2 - Wikipedia

    en.wikipedia.org/wiki/KLRC2

    KLRC2 has been shown to interact and form dimers with CD94. [5] [6] The CD94/NKG2C heterodimer can bind to HLA-E [7] [8] and this binding leads to NK cells activation.During infection with human cytomegalovirus, peptides derived from the virus are presented on HLA-E and natural killer cells that express the CD94/NKG2C receptor can specifically recognise the virus peptides.

  5. Killer-cell immunoglobulin-like receptor - Wikipedia

    en.wikipedia.org/wiki/Killer-cell_immunoglobulin...

    Natural killer (NK) cells are a type of lymphocyte cell involved in the innate immune system's response to viral infection and tumor transformation of host cells. [20] [7] Like T cells, NK cells have many qualities characteristic of the adaptive immune system, including the production of “memory” cells that persist following encounter with antigens and the ability to create a secondary ...

  6. Adaptive NK cell - Wikipedia

    en.wikipedia.org/wiki/Adaptive_NK_cell

    An adaptive natural killer (NK) cell or memory-like NK cell is a specialized natural killer cell that has the potential to form immunological memory. [ 1 ] [ 2 ] They can be distinguished from cytotoxic NK (cNK) cells by their receptor expression profile and epigenome. [ 3 ]

  7. Innate immune system - Wikipedia

    en.wikipedia.org/wiki/Innate_immune_system

    The innate leukocytes include: natural killer cells, mast cells, eosinophils, basophils; and the phagocytic cells include macrophages, neutrophils, and dendritic cells, and function within the immune system by identifying and eliminating pathogens that might cause infection. [2]

  8. AOL Mail

    mail.aol.com

    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. HLA-E - Wikipedia

    en.wikipedia.org/wiki/HLA-E

    HLA-E has a very specialized role in cell recognition by natural killer cells (NK cells). [7] HLA-E binds a restricted subset of peptides derived from signal peptides of classical MHC class I molecules, namely HLA-A, B, C, G. [8] These peptides are released from the membrane of the endoplasmic reticulum (ER) by the signal peptide peptidase and trimmed by the cytosolic proteasome.