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γ-Hydroxybutyric acid, also known as gamma-hydroxybutyric acid, GHB, or 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a depressant drug.It is a precursor to GABA, glutamate, and glycine in certain brain areas.
The GI cocktail is a mixture of a viscous anesthetic, an antacid, and an anticholinergic. [1] [2] Common viscous anesthetics use are viscous lidocaine or xylocaine.Common antacids used are magnesium hydroxide, aluminum hydroxide, or simethicone (more commonly known as Mylanta or Maalox). [3]
GHB has biphasic effects, a euphoric effect at low doses (the reason for the term liquid ecstasy), and a sedative effect [37] at higher doses. As a result of this sedation it can cause unconsciousness. [38] When combined with alcohol the increased sedation and risk of vomiting results in a high risk of fatality. Many harm reduction ...
The term extended to the drug in any form as well as to other drugs with similar effects, e.g. butyl nitrite which is packaged under a variety of trade names in small bottles. [ 52 ] In the late 1970s, Time magazine [ 54 ] and The Wall Street Journal [ 55 ] reported that popper use among gay men began as a way to enhance sexual pleasure, but ...
Drug administration via the nasal cavity yields rapid drug absorption and therapeutic effects. [33] This is because drug absorption through the nasal passages does not go through the gut before entering capillaries situated at tissue cells and then systemic circulation and such absorption route allows transport of drugs into the central nervous ...
The Food and Drug Administration has issued warnings about multiple ... Mills adds. Tadalafil is an extremely potent treatment for erectile dysfunction − but it can have severe side effects ...
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Today's NYT Connections puzzle for Sunday, December 15, 2024The New York Times