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Burkholderia pseudomallei [a] (also known as Pseudomonas pseudomallei) is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. [2] It is a soil-dwelling bacterium endemic in tropical and subtropical regions worldwide, particularly in Thailand and northern Australia. [ 3 ]
Burkholderia mallei and B. pseudomallei have a history of being on a list of potential biological warfare agents. The Centers for Disease Control and Prevention classifies B. mallei as a category B critical biological agent. [7] As a result, research regarding B. mallei may only be done in biosafety level 3 facilities in the US and internationally.
Melioidosis is an infectious disease caused by a gram-negative bacterium called Burkholderia pseudomallei. [1] Most people exposed to B. pseudomallei experience no symptoms; however, those who do experience symptoms have signs and symptoms that range from mild, such as fever and skin changes, to severe with pneumonia, abscesses, and septic shock that could cause death. [1]
Burkholderia is a genus of Pseudomonadota whose pathogenic members include the Burkholderia cepacia complex, which attacks humans and Burkholderia mallei, responsible for glanders, a disease that occurs mostly in horses and related animals; Burkholderia pseudomallei, causative agent of melioidosis; and Burkholderia cepacia, an important pathogen of pulmonary infections in people with cystic ...
It includes some pathogenic species, such as Burkholderia mallei and Burkholderia pseudomallei (melioidosis). [5] This family was found to be enriched in scale-eating pupfish (Cyprinodon desquamator) guts, even after being fed a common laboratory diet, suggesting it may aid in scale-digestion (Heras and Martin 2022).
Colonies of Burkholderia pseudomallei, one of many pathogenic Betaproteobacteria. Scientific classification; Domain: Bacteria: Phylum: Pseudomonadota: Class: Betaproteobacteria: Orders Burkholderiales Ferritrophicales Ferrovales Neisseriales Nitrosomonadales Procabacteriales Rhodocyclales
The Burkholderiales are an order of Betaproteobacteria in the phylum Pseudomonadota. [3] Like all Pseudomonadota, they are Gram-negative.They include several pathogenic bacteria, including species of Burkholderia, Bordetella, and Ralstonia. [3]
Burkholderia thailandensis is a nonfermenting motile, Gram-negative bacillus that occurs naturally in soil. It is closely related to Burkholderia pseudomallei , but unlike B. pseudomallei , it only rarely causes disease in humans or animals.