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Other first-line treatment options for blood pressure and heart disease are now considered before Viagra. ... Sildenafil’s ability to increase blood flow makes the medication useful for managing ...
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
Viagra works by improving blood flow to your privates. The active ingredient, Sildenafil, is a PDE5 inhibitor that helps blood vessels relax. This helps improve blood flow to the privates, making ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
Viagra or sildenafil, the active ingredient and generic version, is a PDE-5 inhibitor that widens blood vessels inside the member to allow better blood flow for stronger or longer-lasting arousal.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Figure 3. A flow chart showing the relationship between different parts (domains) of PDE5-inhibitors. Figure 4. A representation of the 3D structure of sildenafil, a common PDE5-inhibitor. The PDE5 inhibitors sildenafil, vardenafil and tadalafil are competitive and reversible inhibitors of cGMP hydrolysis by the catalytic side of PDE5.
Research has found that taking Viagra does not increase high blood pressure. Sildenafil, the active ingredient in Viagra, is actually used to treat a certain kind of high blood pressure in the lungs.
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