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  2. p53 - Wikipedia

    en.wikipedia.org/wiki/P53

    p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers. The p53 proteins (originally thought to be, and often spoken of as, a single protein) are crucial in vertebrates , where they prevent cancer formation. [ 5 ]

  3. Induced pluripotent stem cell - Wikipedia

    en.wikipedia.org/wiki/Induced_pluripotent_stem_cell

    Embryoid body: hESCs in culture spontaneously form ball-like embryo-like structures termed "embryoid bodies", which consist of a core of mitotically active and differentiating hESCs and a periphery of fully differentiated cells from all three germ layers. iPSCs also form embryoid bodies and have peripheral differentiated cells.

  4. P53 p63 p73 family - Wikipedia

    en.wikipedia.org/wiki/P53_p63_p73_family

    P53, p63, and p73 have similar features in their gene structures and functions but have also diverged evolutionarily. The p53 family evolved from an ancestor gene in unicellular life. [ 4 ] The ancestor gene functioned in germ line DNA protection early invertebrates. [ 5 ]

  5. Hematopoietic stem cell - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell

    Hematopoietic stem cells (HSCs) are the stem cells [1] that give rise to other blood cells.This process is called haematopoiesis. [2] In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition.

  6. Human papillomavirus infection - Wikipedia

    en.wikipedia.org/wiki/Human_papillomavirus_infection

    In short, p53 is a tumor-suppressor protein that arrests the cell cycle and prevents cell growth and survival when DNA damage occurs. [48] Thus, the degradation of p53, induced by E6, promotes unregulated cell division, cell growth and cell survival, all characteristics of cancer.

  7. TP53BP1 - Wikipedia

    en.wikipedia.org/wiki/TP53BP1

    Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene. [5] [6] [7] Clinical ...

  8. Your Cholesterol Could Be A Key Indicator Of Dementia. A ...

    www.aol.com/lifestyle/cholesterol-could-key...

    Typically, dementia is associated with classic symptoms like confusion and memory loss. But new research finds that there could be a less obvious risk factor out there: your cholesterol levels ...

  9. Embryonic stem cell - Wikipedia

    en.wikipedia.org/wiki/Embryonic_stem_cell

    AST-OPC1 is a population of cells derived from human embryonic stem cells (hESCs) that contains oligodendrocyte progenitor cells (OPCs). OPCs and their mature derivatives called oligodendrocytes provide critical functional support for nerve cells in the spinal cord and brain.