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N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) is an enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE). This is a major part of the process that converts ordinary lipids into chemical signals like anandamide and oleoylethanolamine .
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name 'N-acetylphosphatidylethanolamine phosphatidohydrolase. [1] [2] It catalyses the following chemical reaction
A hydrophobic cavity in NAPE-PLD provides an entryway for the substrate NAPE into the active site, where a binuclear zinc center orchestrates its hydrolysis. Unexpectedly, the structure unveils bile acids bind the membrane enzyme, enhancing dimer assembly and enabling catalysis.
NAPE-PLD may refer to: N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [ wikidata ] N-acyl phosphatidylethanolamine-specific phospholipase D , an enzyme
The uncovered nape of a maiko 's neck Cat carrying a kitten by its nape, known as the "scruff". The nape is the back of the neck.In technical anatomical/medical terminology, the nape is also called the nucha (from the Medieval Latin rendering of the Arabic نُخَاع, ' spinal marrow ').
The style required that the hair were combed back around the sides of the head. The teeth edge of a comb was then used to define a central parting flowing from the crown to the nape at the back of the head, resembling, to many, the rear end of a duck. The hair on the top front of the head was usually that of a pompadour.
The German National Action Plan on Energy Efficiency (NAPE) (German: Nationaler Aktionsplan Energieeffizienz) is the National Energy Efficiency Action Plan (NEEAP) for Germany. [1] The plan was commissioned under EU Energy Efficiency Directive 2012/27/EU of the European Union and released on 3 December 2014. [ 2 ]
NAPE Foundation, a non-profit organization which supports disadvantaged students in Ghana Newfoundland Association of Public and Private Employees , a union in Newfoundland & Labrador Topics referred to by the same term