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  2. Raynaud syndrome - Wikipedia

    en.wikipedia.org/wiki/Raynaud_syndrome

    A more recent treatment for severe Raynaud's is the use of botulinum toxin. The 2009 article [36] studied 19 patients ranging in age from 15 to 72 years with severe Raynaud's phenomenon of which 16 patients (84%) reported pain reduction at rest; 13 patients reported immediate pain relief, three more had gradual pain reduction over 1–2 months ...

  3. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.

  4. Sclerodactyly - Wikipedia

    en.wikipedia.org/wiki/Sclerodactyly

    Sclerodactyly is one component of the limited cutaneous form of systemic sclerosis (lcSSc), also known as CREST syndrome (CREST is an acronym that stands for calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.) [4] Sclerodactyly is also one component of Huriez Syndrome, along with palmoplantar ...

  5. Largest ever genetic study of Raynaud's phenomenon ... - AOL

    www.aol.com/news/study-pinpoints-genes-behind...

    Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...

  6. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Mixed_connective_tissue...

    The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...

  7. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Cardiovascular: Raynaud's phenomenon (is the presenting symptom in 30% of affected persons, occurs in 95% of affected individuals at some time during their illness); healed pitting ulcers on the fingertips; skin and mucosal telangiectasis; palpitations, irregular heart rate and fainting due to conduction abnormalities, hypertension, and ...

  8. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

  9. Skin temperature - Wikipedia

    en.wikipedia.org/wiki/Skin_temperature

    Raynaud's phenomenon (also known as Raynaud's disease or syndrome) is an important condition affecting skin temperature of many around the globe. [35] Raynaud's phenomenon is the exaggerated response of cutaneous circulation to exposure to cold ambient temperatures. [36] ‘Raynaud attacks’, which can begin in parts of the body and spread ...