enow.com Web Search

Search results

1. Results from the WOW.Com Content Network

2. Trazodone - Wikipedia

   en.wikipedia.org/wiki/Trazodone

   Trazodone has a minor active metabolite known as meta-chlorophenylpiperazine (mCPP), and this metabolite may contribute to some degree to the pharmacological properties of trazodone. [11] [110] In contrast to trazodone, mCPP is an agonist of various serotonin receptors. [111]

3. Substituted piperazine - Wikipedia

   en.wikipedia.org/wiki/Substituted_piperazine

   Trazodone, nefazodone, mepiprazole, and others produce mCPP as a metabolite. para-Substituted. 4-Chlorophenylpiperazine (pCPP) 4-Fluorophenylpiperazine (pFPP)

4. meta-Chlorophenylpiperazine - Wikipedia

   en.wikipedia.org/wiki/Meta-Chlorophenylpiperazine

   [2] [51] [52] The elimination half-life of mCPP is 4 to 14 hours. [2] mCPP is a metabolite of a variety of other piperazine drugs including trazodone, nefazodone, etoperidone, enpiprazole, mepiprazole, cloperidone, peraclopone, and BRL-15,572. [52] [additional citation(s) needed] It is formed by dealkylation via CYP3A4. [52]

5. What is Compounded Tirzepatide? Here's What You Need to Know

   www.aol.com/compounded-tirzepatide-heres-know...

   What Is Compounded Tirzepatide? This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. If you’re starting a weight loss journey, you might have stumbled upon tirzepatide — the drug ...

6. Trump seeks fast appointments; Elon Musk makes endorsement ...

   www.aol.com/news/elon-musk-endorses-republican...

   (Reuters) -Businessman Elon Musk, an ally of President-elect Donald Trump, endorsed Republican Senator Rick Scott for U.S. Senate majority leader on Sunday as Trump pushed candidates for the ...

7. The Zepbound Shortage Is Over — Here's What to Expect ... - AOL

   www.aol.com/zepbound-shortage-over-heres-expect...

   Eli Lilly’s weight loss drug Zepbound is no longer in short supply, the FDA said, worrying patients who use cheaper, off-brand versions of the drug. On Thursday, Dec. 19, the U.S. Food and Drug ...

8. Serotonin antagonist and reuptake inhibitor - Wikipedia

   en.wikipedia.org/wiki/Serotonin_antagonist_and...

   These drugs act as antagonists or inverse agonists of the 5-HT 2A, α 1-adrenergic, and H 1 receptors, as partial agonists of the 5-HT 1A receptor, [3] and as inhibitors of the transporters. mCPP is an antagonist of the 5-HT 2B receptor, an agonist of the 5-HT 1A, [3] 5-HT 2C, and 5-HT 3 receptors, [4] [5] and acts as a partial agonist of the ...

9. 5-HT2C receptor agonist - Wikipedia

   en.wikipedia.org/wiki/5-HT2c_receptor_agonist

   The serotonin receptor agonist mCPP has a significant affinity for 5-HT 2C receptors. mCPP patients experience multiple side effects due to non-selectivity over 5-HT 2A and 5-HT 2B receptors. The absence of the hypophagic (reduced food consumption) effect of mCPP in 5-HT 2C receptor knockout mice suggests that this effect is mediated through 5 ...