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Most Pax genes contain a homeobox and a paired domain that also binds DNA to increase binding specificity, though some Pax genes have lost all or part of the homeobox sequence. [46] Pax genes function in embryo segmentation, nervous system development, generation of the frontal eye fields, skeletal development, and formation of face structures.
Homeobox containing 1, also known as homeobox telomere-binding protein 1 (HOT1), is a protein that in humans is encoded by the HMBOX1 gene. [5] HMBOX1 directly binds to the double-stranded repeat sequence of telomeres .
3211 15407 Ensembl ENSG00000120094 ENSMUSG00000018973 UniProt P14653 P17919 RefSeq (mRNA) NM_002144 NM_008266 RefSeq (protein) NP_002135 NP_032292 Location (UCSC) Chr 17: 48.53 – 48.53 Mb Chr 11: 96.26 – 96.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. Function This gene belongs to the homeobox ...
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17 . The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized ...
Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene. [5] [6] [7] This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene ...
Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene. [5] [6] [7] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ...
Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene. [5] [6] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ...
Ladybird homeobox 2 (LBX2) is a protein that is encoded by the LBX2 gene, located on the second chromosome [5] in humans, and on the sixth chromosome in mice. [ 6 ] LBX2 belongs to the homeobox gene family, which plays important roles in embryonic development and tissue differentiation.