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Grape seed extract is an industrial derivative of whole grape seeds. The extract (GSPE) contains proanthocyanidins. [1] Grape seed extract quality is measured by the content of procyanidins which are formed from proanthocyanidins. [2] Generally, grape seed extract quality contains 95% procyanidins, but potency varies among products. [3]
They are dense in grape seeds and skin, and therefore in red wine and grape seed extract, cocoa, nuts and all Prunus fruits (most concentrated in the skin), and in the bark of Cinnamomum [4] and Pinus pinaster (pine bark; formerly known as Pinus maritima), along with many other pine species.
Procyanidin C2 is the subtype of extract most effective. [11] Experiments showed that both procyanidin C2 and Pycnogenol (French maritime pine bark extract) increase TNF-α secretion in a concentration- and time-dependent manner. These results demonstrate that procyanidins act as modulators of the immune response in macrophages.
In the late 20th century interest in the possible health benefits of resveratrol in wine was spurred by discussion of the French paradox involving the health of wine drinkers in France. [ 32 ] Piceatannol is also present in grape [ 33 ] from where it can be extracted and found in red wine.
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The concept of vinotherapy was expanded by Mathilde and Bertrand Thomas. The French couple learned about the impact of grape seeds from the leading expert on grape and grapevine polyphenols Dr. Vercauteren. [1] In 1995, Mathilde and Bertrand launched a line of Vinothérapie skincare products made from grape derived ingredients: Caudalie.
Eating a diet rich in fish and other seafood has several benefits due to its nutrient profile (rich in vitamin D and omega-3 fatty acids), protein content, and low-calorie density.
Grapefruit seed extract (GSE), also known as citrus seed extract, is a liquid extract derived from the seeds, pulp, and white membranes of grapefruit. [1] GSE is prepared by grinding the grapefruit seed and juiceless pulp, then mixing with glycerin . [ 1 ]
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