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[30] [31] Thoracic blood pressure rises and as a reflex response the amount of blood pumped by the heart decreases. Death has been known to occur in cases where defecation causes the blood pressure to rise enough to cause the rupture of an aneurysm or to dislodge blood clots (see thrombosis). Also, in releasing the Valsalva maneuver blood ...
At the anus, there are two anal sphincters which control the exit of feces from the body, the internal anal sphincter and external anal sphincter. The inner sphincter is involuntary and the outer is voluntary. The microscopic precapillary sphincters function to control the blood flow into each capillary in response to local metabolic activity. [1]
Venous blood can once more enter the chest and the heart; cardiac output increases. Return of cardiac output Blood return to the heart is enhanced by the effect of the entry of blood that has been dammed back, causing a rapid increase in cardiac output (24 seconds on). The stroke volume usually rises above normal before returning to a normal level.
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Blood flows, Q, and concentration, [X], of a substance of interest are depicted. Physiologically based pharmacokinetic (PBPK) modeling is a mathematical modeling technique for predicting the absorption, distribution, metabolism and excretion (ADME) of synthetic or natural chemical substances in humans and other animal species.
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Flow (stylized as flOw) is an independent video game created by Jenova Chen and Nicholas Clark. Originally released as a free Flash game in 2006 to accompany Chen's master's thesis , it was reworked into a 2007 PlayStation 3 game by his development studio, Thatgamecompany , with assistance from Santa Monica Studio .
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