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  2. Suzetrigine - Wikipedia

    en.wikipedia.org/wiki/Suzetrigine

    Suzetrigine has already been granted FDA Fast Track and Breakthrough Therapy designations for the treatment of moderate-to-severe acute pain. [5] Vertex Pharmaceuticals also plans to seek a broad label for peripheral neuropathic pain, citing positive phase 2 results in painful diabetic peripheral neuropathy (DPN). [3]

  3. Diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_neuropathy

    A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [1] Diabetic neuropathy is implicated in 50–75% of nontraumatic amputations. The main risk factor for diabetic neuropathy is hyperglycemia. In the DCCT (Diabetes Control and Complications Trial, 1995) study, the annual incidence of neuropathy ...

  4. Proximal diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Proximal_diabetic_neuropathy

    Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.

  5. Complications of diabetes - Wikipedia

    en.wikipedia.org/wiki/Complications_of_diabetes

    Diabetic neuropathy, Neuropathies in diabetes may cause sensory, mononeuritis, and autonomic neuropathy symptoms, muscle weakness, and potentially life-threatening complications like diabetic foot syndrome (Diabetic amyotrophy) and myocardial infarctions. Intensive insulin therapy is recommended to reduce neuropathy risk, while oral ...

  6. Breakthrough test could predict deadly diseases in people ...

    www.aol.com/breakthrough-test-could-predict...

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  7. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    medical obesity caused by proopiomelanocortin , proprotein convertase subtilisin/kexin type 1 , or leptin receptor deficiency Pralsetinib: Blueprint Medicines Corp: RET-mutant medullary thyroid cancer or advanced or metastatic RET fusion-positive thyroid cancer, in radioactive iodine-refractory patients [2] Belimumab: GlaxoSmithKline

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