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Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. [1] The colloid is coloured usually either wine red (for spherical particles less than 100 nm) or blue-purple (for larger spherical particles or nanorods). [2]
Gold nanoparticles in chemotherapy and radiotherapy is the use of colloidal gold in therapeutic treatments, often for cancer or arthritis. Gold nanoparticle technology shows promise in the advancement of cancer treatments.
Gold nanoparticles can be purchased or synthesized via a variety of methods. [12] Several strategies exist for functionalizing gold nanoparticles with single-stranded DNA; one of the most commonly utilized strategies involves introducing thiol-terminated DNA to a solution of gold nanoparticles and gradually increasing the concentration of a salt, like NaCl.
The actual production of the nanoparticles involves pumping "silicone oil, a mixture of gold-seeded silica particles and gold-plating solution and reducing agent solution to the microfluidic device while nitrogen gas was delivered from a cylinder." [5] The plating solution was then left to age, in a controlled environment, for longer than 24 ...
Nanocarriers discovered include polymer conjugates, polymeric nanoparticles, lipid-based carriers, dendrimers, carbon nanotubes, and gold nanoparticles. Lipid-based carriers include both liposomes and micelles. Examples of gold nanoparticles are gold nanoshells and nanocages. [3]
Whereas gold nanoparticles absorb light in the visible spectrum of light (at about 550 nm), gold nanocages absorb light in the near-infrared, [2] where biological tissues absorb the least light. Because they are also biocompatible, gold nanocages are promising as a contrast agent for optical coherence tomography.
A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter. [1] [2] The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions.
Gold nanoparticles have been used in the past for pharmaceutical and medical uses, but only recently have cosmetic brands sought patents for gold nanoparticles to use them for cosmetic formulation. Research conducted by Tatsiana Mironava, PhD, from Stony Brook University concluded that the size, concentration and frequency of application plays ...