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  2. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Vitamin K1-warfarin interaction effect: When warfarin levels are high, people have more risk of bleeding. Conversely, lower levels of warfarin lead to increased risk of blood clots. A narrow range exists where the benefits of warfarin are greater than the risks, its therapeutic window. Certain drugs, herbal medicines, and foods can interact ...

  3. Bristol-Myers Squibb and Pfizer Announce Publication of ...

    www.aol.com/news/2013-05-06-bristol-myers-squibb...

    Bristol-Myers Squibb and Pfizer Announce Publication of ARISTOTLE Subanalysis in Circulation Subgroup analysis demonstrates that the treatment effects of Eliquis ® (apixaban) vs. warfarin, across ...

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    [6] [7] [8] It is used as an alternative to warfarin to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [6] [8] and does not require monitoring by blood tests [6] or dietary restrictions. [9] It is taken by mouth. [6] Common side effects include bleeding and nausea.

  5. Subanalysis of Phase III ARISTOTLE Trial of Eliquis ... - AOL

    www.aol.com/news/2013-09-03-subanalysis-of-phase...

    Subanalysis of Phase III ARISTOTLE Trial of Eliquis® (apixaban) Demonstrated Consistent Results Versus Warfarin in Patients with Nonvalvular Atrial Fibrillation with or without Valvular Heart ...

  6. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  7. U.S. FDA Approves ELIQUIS® (apixaban) to Reduce the ... - AOL

    www.aol.com/news/2013-01-02-us-fda-approves...

    U.S. FDA Approves ELIQUIS ® (apixaban) to Reduce the Risk of Stroke and Systemic Embolism in Patients with Nonvalvular Atrial Fibrillation ELIQUIS Demonstrated Superior Risk Reductions Versus ...

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