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  2. Popular dog arthritis medication Librela linked to pet ... - AOL

    www.aol.com/popular-dog-arthritis-medication...

    A popular arthritis medication for dogs has sickened thousands of pets and likely caused others to die, the Food and Drug Administration said in an urgent warning. Dangerous side effects from the ...

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  4. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban bears a striking structural similarity to the antibiotic linezolid: both drugs share the same oxazolidinone-derived core structure. [39] Accordingly, rivaroxaban was studied for any possible antimicrobial effects and for the possibility of mitochondrial toxicity, which is a known complication of long-term linezolid use. [40]

  5. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  6. 7 Alternatives to Chemotherapy for Lymphoma in Dogs - AOL

    www.aol.com/7-alternatives-chemotherapy-lymphoma...

    1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...

  7. Skin conditions in dogs: Symptoms, causes, and how to help - AOL

    www.aol.com/skin-conditions-dogs-symptoms-causes...

    A vet explains the most common skin conditions in dogs and the ... and have the advantage of minimal side effects elsewhere in the body. ... low levels in most dogs, not usually causing a problem ...

  8. Polysulfated glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Polysulfated_glycosaminoglycan

    The glycosaminoglycan side chains are polyanionic, which causes adjacent side chains to push each other away and create a "bottle brush", where hyaluronic acid is the stem and the side chains are the bristles. When pressure is exerted on the joint, fluids move between the chondrocytes and synovial fluid, exchanging nutrients. [4]

  9. Benadryl for Dogs? A Vet Explains How Much You Should Give - AOL

    www.aol.com/benadryl-dogs-vet-explains-much...

    Related: Benadryl for Dogs: Side Effects of Long-Term Use Signs of Benadryl Overdose in Dogs At normal doses, Benadryl is quite safe, but a survey of over 600 dogs (1) found the following signs of ...

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