Search results
Results from the WOW.Com Content Network
Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. [2] This resistance affects all classes of microbes, including bacteria (antibiotic resistance), viruses (antiviral resistance), protozoa (antiprotozoal resistance), and fungi (antifungal ...
Deadliest Enemy: Our War Against Killer Germs is a non-fiction book by epidemiologist Michael T. Osterholm and writer Mark Olshaker, that explores public health emergencies including antimicrobial resistance, emerging infectious disease, and the threat of an influenza pandemic. It proposes a nine-point "battle plan for survival" for dealing ...
Every time an antimicrobial agent is used, it applies selection evolutionary pressure to microbial populations which can result in disruption to the normal microbiome as well as resistance to that agent, and even cross-resistance to other agents. Resistance can then spread to other microbes and to other host organisms.
This scenario has stimulated the research for an alternative strategy focused on agents (antivirulence or antipathogenic agents) aimed to disarm microorganisms cause of infectious disease, without killing or inhibiting the growth of microorganisms themselves and therefore with limited selective pressure to promote the antibiotic resistance ...
The One Health Trust's ResistanceMap is a collection of tools summarizing national and subnational data on antimicrobial use and resistance globally. [30] Since its launch in 2010, ResistanceMap has been used to inform researchers, policy makers, and the public of important trends in drug resistance and antibiotic use. [31] [32]
He led the first, and perhaps only, prospective farm study showing that feed containing low dose antibiotics led to the emergence of antibiotic resistance in animals and the farm family. [2] He has published over 300 papers, edited four books and two special journal editions devoted to antibiotic use and resistance. [2]
In addition to developing new antibacterial treatments, it is important to reduce the selection pressure for the emergence and spread of antimicrobial resistance (AMR), such as antibiotic resistance. Strategies to accomplish this include well-established infection control measures such as infrastructure improvement (e.g. less crowded housing ...
Antimicrobial resistance and antineoplastic resistance challenge clinical care and drive research. When an organism is resistant to more than one drug, it is said to be multidrug-resistant. The development of antibiotic resistance in particular stems from the drugs targeting only specific bacterial molecules (almost always proteins).