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The Portfolio Diet is a therapeutic plant-based diet created by British researcher David J. Jenkins in 2003 to lower blood cholesterol. [1] [2] The diet emphasizes using a portfolio of foods or food components that have been found to associate with cholesterol lowering to enhance this effect.
Trials looking at high doses (> 4 g/day) of plant sterols or stanols are very limited, and none have yet to be completed comparing the same high dose of plant sterol to plant stanol. The debate regarding sterol vs. stanol safety is centered on their differing intestinal absorption and resulting plasma concentrations.
However, in contrast to FH patients, sitosterolemia patients usually have normal to moderately elevated total sterol levels and very high levels of plant sterols (sitosterol, campesterol, stigmasterol, avenosterol) and 5α-saturated stanols in their plasma. Plasma sitosterol levels in sitosterolemia patients are 10–25 times higher than in ...
β-Sitosterol is widely distributed in the plant kingdom.It is found in vegetable oil, nuts, avocados, and derived prepared foods such as salad dressings. [2] Olavius algarvensis, a species of marine annelid, predominantly incorporate β-sitosterol into their cell membranes instead of cholesterol, though cholesterol is also present in said membranes.
Plant sterols were first shown in the 1950s to lower LDLs and cholesterol. [7] Since then, numerous studies have reported the lipid-lowering effects of dietary phytosterols, including campesterol. [8] In basic research, campesterol competes with cholesterol, thus reducing the absorption of cholesterol in the human intestine. [9]
Sterol is an organic compound [1] with formula C 17 H 28 O , whose molecule is derived from that of gonane by replacement of a hydrogen atom on C3 position by a hydroxyl group.
Experts recommend a plant-based diet high in soluble fiber – oatmeal, oat bran, beans, apples, peas, citrus fruits, carrots, barley, flaxseed, a gel-forming powder called psyllium, as well as ...
Stigmasterol – a plant sterol (phytosterol) – is among the most abundant of plant sterols, having a major function to maintain the structure and physiology of cell membranes. [2] In the European Union , it is a food additive listed with E number E499 , and may be used in food manufacturing to increase the phytosterol content, potentially ...
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