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In 1977, Hobson and McCarley developed the activation synthesis theory of dreaming that said that dreams do not have meanings and are the result of the brain attempting to make sense of random neuronal firing in the cortex. [2] McCarley has extensively studied the brainstem mechanisms that control REM sleep. [3]
The bunker experiment was a scientific experiment that began in 1966 to test whether humans, like other species, have an intrinsic circadian clock. [1] It was started by Jürgen Aschoff and Rütger Wever of the Max Planck Institute for Behavioral Physiology and later taken over by Jürgen Zulley.
Nathaniel Kleitman (April 26, 1895 – August 13, 1999) [1] [2] was an American physiologist and sleep researcher who served as Professor Emeritus in Physiology at the University of Chicago. He is recognized as the father of modern sleep research, and is the author of the seminal 1939 book Sleep and Wakefulness.
The circadian rhythm provides a person with a signal for when to sleep and when to wake up. [43] If circadian rhythm and sleep-wake cycle are misaligned, this might lead to negative affect and emotional instability. [44] It has been found that emotions vary depending on the circadian rhythm and the duration of how long one was awake. [45]
The cognitive shuffle is based on Beaudoin’s somnolent information processing theory. [5] [13] The somnolent information processing theory postulates the existence of a sleep onset control system that evolved to ensure that falling asleep tends to happen when it is evolutionarily opportune (safe, timely) to fall asleep. [14]
After sustained periods of sleep, both the speed and synchronicity of the neurons firing are shown to decrease. [5] Another effect of wakefulness is the reduction of glycogen held in the astrocytes, which supply energy to the neurons. Studies have shown that one of sleep's underlying functions is to replenish this glycogen energy source. [6]
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Free-running sleep is a rare sleep pattern whereby the sleep schedule of a person shifts later every day. [1] It occurs as the sleep disorder non-24-hour sleep–wake disorder or artificially as part of experiments used in the study of circadian and other rhythms in biology .