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Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8] It is used either by mouth or injection into a muscle. [8] Hydroxyzine works by blocking the effects of histamine. [9]
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
Vistaril (hydroxyzine) – an antihistamine for the treatment of itches and irritations, an antiemetic, as a weak analgesic, an opioid potentiator, and as an anxiolytic; Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo
These compounds are structurally related to the ethylenediamines and the ethanolamines, and produce significant anticholinergic adverse effects with the exception of hydroxyzine, which has low to no affinity for muscarinic acetylcholine receptors and therefore produces negligible anticholinergic side-effects. [16]
It seriously underestimates the incidence of major side effects from this drug. First of all, like many first-generation antihistamines, Hydroxyzine has significant anticholinergic effects. It is a potent delirogenic drug in the elderly, particularly in the elderly in cognitive decline (suffering from diagnosed, or in many cases undiagnosed ...
In combination with neostigmine to prevent muscarinic effects such as bradycardia; Sialorrhea; Hyperhidrosis; COPD; Dry mouth; UR; Headache; Vomiting; Does not cross the blood–brain barrier and has few to no central effects. [9] Robinul, Cuvposa, Seebri Hydroxyzine: Very mild/negligible action Vistaril, Atarax Ipratropium bromide NS: Asthma ...
This drug has been withdrawn from the market in most countries. Hydroxyzine and secobarbital lengthen the half-life of brallobarbital. Because of this long half-life, it has symptoms resembling a hangover on the next day.
Hydroxyzine (Atarax) is an antihistamine originally approved for clinical use by the FDA in 1956. Hydroxyzine has a calming effect which helps ameliorate anxiety. Hydroxyzine efficacy is comparable to benzodiazepines in the treatment of generalized anxiety disorder. [41]
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