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  2. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [5]

  3. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    The presence of uric acid crystals in joint tissue is what leads to the inflammation and pain associated with gout. Levels of uric acid can rise for different things. For instance, due to genetic ...

  4. Calcium pyrophosphate dihydrate crystal deposition disease

    en.wikipedia.org/wiki/Calcium_pyrophosphate_di...

    Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]

  5. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]

  6. Gout, a painful form of arthritis, is on the rise. Avoiding ...

    www.aol.com/lifestyle/gout-painful-form...

    Uric acid forms crystals around joints in the body, most commonly in the big toe or knee, but can be found in any joint. When this occurs, the affected joint results in severe pain, swelling and ...

  7. Common Causes of Arthritis for Women (& How to Treat It) - AOL

    www.aol.com/common-causes-arthritis-women-treat...

    Analysis of a sample of synovial fluid to look for signs of an infection (infectious arthritis) or uric acid crystals (gout) Imaging tests, such as X-rays or MRI scans, to evaluate the condition ...

  8. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...

  9. Hyperuricemia - Wikipedia

    en.wikipedia.org/wiki/Hyperuricemia

    Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...

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