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Early detection critical to long-term breast cancer survival. The ongoing OlympiA trial involves more than 1,800 adults diagnosed with gBRCAm, HER2-negative high-risk early breast cancer, early ...
The supermodel explained that a doctor called her after she had a lumpectomy and told her it was HER2 positive estrogen receptive intraductal carcinoma, which is a type of breast cancer, per the ...
The approach is similar to that of late "Grease" star Olivia Newton-John, from whom Macpherson sought advice after the actor famously complemented her clinical treatment for breast cancer with ...
In the United States, trastuzumab emtansine was approved specifically for treatment of HER2-positive metastatic breast cancer (mBC) in patients who have been treated previously with trastuzumab and a taxane (paclitaxel or docetaxel), and who have already been treated for mBC or developed tumor recurrence within six months of adjuvant therapy.
As of November 2015, there are a number of ongoing and recently completed clinical trials of novel targeted agents for HER2+ metastatic breast cancer, e.g. margetuximab. [36] Additionally, NeuVax (Galena Biopharma) is a peptide-based immunotherapy that directs "killer" T cells to target and destroy cancer cells that express HER2. It has entered ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
The Office alum shared on Oct. 8 that she was diagnosed with stage I triple-positive breast cancer on Dec. 1, 2023, and over the past few months, underwent a lumpectomy, chemotherapy and radiation ...
NeuVax has been tested as adjuvant treatment in nearly 200 breast cancer patients over a total of 5 years, and has shown to be safe and effective in Phase 2 trials. [6] As a result, two additional NeuVax trials registered or underway are: (1) a 700 patient Phase 3 trial for FDA approval - not yet recruiting [2] [needs update] and (2) a 300 patient Phase 2 trial studying the combination of ...
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