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Pegaptanib [2] sodium injection (brand name Macugen) is an anti-angiogenic medicine for the treatment of neovascular (wet) age-related macular degeneration (AMD). [3] It was discovered by NeXstar Pharmaceuticals (which merged with Gilead Sciences in 1999) and licensed in 2000 to EyeTech Pharmaceuticals, now OSI Pharmaceuticals, for late stage development and marketing in the United States.
Ranibizumab, sold under the brand name Lucentis among others, is a monoclonal antibody fragment created from the same parent mouse antibody as bevacizumab.It is an anti-angiogenic [16] that is approved to treat the "wet" type of age-related macular degeneration (AMD, also ARMD), diabetic retinopathy, and macular edema due to branch retinal vein occlusion or central retinal vein occlusion.
Avacincaptad pegol, sold under the brand name Izervay, is a medication used for the treatment of age-related macular degeneration. [1] Avacincaptad pegol is a complement inhibitor. [1] Avacincaptad pegol was approved for medical use in the United States in August 2023. [2] [3] [4]
Tarrytown, N.Y.-based Regeneron said yesterday it has gotten clearance from the FDA to start selling afilbercept. The folks at Regeneron Pharmaceuticals (NAS: REGN) are going to have a happy ...
As with pretty much anything that has to do with the reproductive system, there are (1) potential side effects of taking Plan B and (2) a host of truly bonkers misinformation out there (hi, it’s ...
Off-label use of intravitreal bevacizumab has become a widespread treatment for neovascular age-related macular degeneration. [11] Although the drug is not FDA-approved for non-oncologic uses, some studies [which?] suggest that bevacizumab is effective in increasing visual acuity with low rates of ocular adverse effects. However, due to small ...
The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release. The ...
Common adverse effects of the eye formulation include conjunctival hemorrhage, eye pain, cataract, vitreous detachment, floaters, and ocular hypertension. [11]Aflibercept (Zaltrap) has adverse effects typical of anti-cancer drugs, such as reduced blood cell count (leukopenia, neutropenia, thrombocytopenia), gastrointestinal disorders like diarrhea and abdominal pain, and fatigue.
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