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It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.
The authors examined the link between lifestyle factors like obesity and metabolism and the causes and effects of Alzheimer’s, studying 80 cognitively normal middle-aged participants. The ...
The authors argue that their findings suggest excess fat could increase the risk of Alzheimer’s disease due to inflammation in the brain, and that reducing fat and obesity in midlife could ...
Millions of Americans are at risk of developing dementia, but early detection and proactive measures could help delay its onset and mitigate its effects, according to a new report. The report ...
Only 1–2% of Alzheimer's cases are inherited due to autosomal dominant effects, as Alzheimer's is highly polygenic. When the disease is caused by autosomal dominant variants, it is known as early onset familial Alzheimer's disease, which is rarer and has a faster rate of progression. [17]
Posterior cortical atrophy (PCA), also called Benson's syndrome, is a rare form of dementia which is considered a visual variant or an atypical variant of Alzheimer's disease (AD). [ 1 ] [ 2 ] [ 3 ] The disease causes atrophy of the posterior part of the cerebral cortex , resulting in the progressive disruption of complex visual processing . [ 4 ]
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